The scientific basis for separating neocortical from limbic brain matter rests on solid neuroanatomical, cellular, and empirical grounds. As viewed t… - Thomas Lewis

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The scientific basis for separating neocortical from limbic brain matter rests on solid neuroanatomical, cellular, and empirical grounds. As viewed through the microscope, limbic areas exhibit a far more primitive cellular organization than their neocortical counterparts. Certain radiographic dyes selectively stain limbic structures, thus painting the molecular dissimilarity between the two brains in clean, vivid strokes. One researcher made an antibody that binds to cells of the hippocampus — a limbic component — and found that those same fluorescent markers stuck to all parts of the limbic brain, lighting it up like a biological Christmas tree, without coloring the neocortex at all. Large doses of some medications destroy limbic tissue while leaving the neocortex unscathed, a sharp-shooting feat enabled by evolutionary divergence in the chemical composition of limbic and neocortical cell membranes.

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The dogged implicitness of emotional knowledge, its relentless unreasoning force, prevents logic from granting salvation just as it precludes self-help books from helping. The sheer volume and variety of helf-help paraphernalia testify at once to the vastness of the appetite they address and their inability to satisfy it.

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Encountering an early series of consistent instances can implant an erroneous generality in a child's mind. This mental machinery distills and does not evaluate; it cannot detect whether the larger world runs in accordance with the scheme it has drawn forth from the emotional microcosm of a family. Just as grammatical English emerges from our lips automatically, a structured pattern of emotional relatedness emanates from each of us.

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