It is essential to realize at this point that the formalism to be developed, although we cast it initially primarily in the framework of natural syst… - Robert Rosen

For a long time, people have been trying to characterize or define the notion of system. After all, “systems” are supposed to be what System Theory is about. The results so far have been contradictory and unsatisfactory. This confusion at the foundations has led many to conclude that there is no such thing as a "system" and hence to deny that System Theory is about anything. Even those most sympathetic to the notion have difficulties at this level. The very founders of System Theory did not try to say what a system was; and as for System Theory, they characterized it only obliquely, by saying it comprised all studies of interest to more than one discipline. They thereby begged the entire question.

Perhaps the first lesson to be learned from biology is that there are lessons to be learned from biology.

The point of departure is the measurement problem, as it appears in physics; the manner in which measurements allow us to characterize subsystems; the role of such subsystems as tools in system analysis; and the relationships existing between different ways of perceiving or interacting with the same system. Our conclusions are: (1) there exists no universal family of analytic units appropriate for the treatment of all interactions; (2) there are on the contrary many such families of analytic units, all of which are equally “real” and entitled to be treated on the same footing; (3) the appropriate use of natural interactions can enormously extend the class of physical observables accessible to us; (4) the concept of a model must be formulated, in its most general terms, as the sharing of a subsystem by two otherwise distinct systems, capable of imposing the same dynamic on an appropriate system with which they can both interact. We establish these results through a variety of terminologies which turn out to be equivalent: stability, invariance, symmetry, homeostasis.