a few years ago, researchers noticed a curious phenomenon: people taking metformin were living notably healthier lives — independent, it seemed, of i… - David A. Sinclair

The problem is not just population, it's consumption. And it's not just consumption, it's waste. In comes the food; out goes the effluent. In come the fossil fuels; out go the carbon emissions. In come the petrochemicals; out goes the plastic. On average, Americans consume more than three times the amount of food they need to survive and about 250 times as much water.14 In return, they produce 4.4 pounds of trash each day, recycling or composting only about of a third of it.15 Thanks to things such as cars, planes, big homes, and power-hungry clothes dryers,16 the annual carbon dioxide emissions of an average American are five times as high as the global average. Even the "floor" — below which even monks living in American monasteries typically do not go — is twice the global average.

For Robin Marantz Henig, a columnist at the New York Times, the "bitter truth" about mortality came late in life, after she became a grandparent. "Beneath all the wonderful moments you may be lucky enough to share in and enjoy," she wrote, "your grandchild's life will be a long string of birthdays you will not live to see."3

And so, with all that on the table, what do I do? • I take 1 gram (1,000 mg) of NMN every morning, along with 1 gram of resveratrol (shaken into my homemade yogurt) and 1 gram of metformin.7 • I take a daily dose of vitamin D, vitamin K2, and 83 mg of aspirin. • I strive to keep my sugar, bread, and pasta intake as low as possible. I gave up desserts at age 40, though I do steal tastes. • I try to skip one meal a day or at least make it really small. My busy schedule almost always means that I miss lunch most days of the week. • Every few months, a phlebotomist comes to my home to draw my blood, which I have analyzed for dozens of biomarkers. When my levels of various markers are not optimal, I moderate them with food or exercise. • I try to take a lot of steps each day and walk upstairs, and I go to the gym