To really achieve anything, you have to be able to tolerate and enjoy risk. It has to become a challenge to look forward to. In all fields, to make exceptional discoveries you need risk — you’re just never going to have a breakthrough without it.

To become original, you have to try something new, which means accepting some measure of risk.

Above all, it's creative thinking that lies at the basis of discoveries. You must dare to think differently, see things from different sides, in order to come across fortuitous new ideas frequently. You should develop even the most stupid ideas and when you do this systematically, there will always come something useful out of it.

Discovery is dangerous . . . but so is life. A man unwilling to take risk is
doomed never to learn, never to grow, never to live.

If you’re interested in mastery,” says University of Cambridge, England, neuropsychologist Barbara Sahakian, “you have to learn this lesson. To really achieve anything, you have to be able to tolerate and enjoy risk. It has to become a challenge to look forward to. In all fields, to make exceptional discoveries you need risk — you’re just never going to have a breakthrough without it.

Our real discoveries come from chaos, from going to the place that looks wrong and stupid and foolish.

My own beliefs are that the road to a scientific discovery is seldom direct, and that it does not necessarily require great expertise. In fact, I am convinced that often a newcomer to a field has a great advantage because he is ignorant and does not know all the complicated reasons why a particular experiment should not be attempted.

Discoveries are often made by not following instructions, by going off the main road, by trying the untried. — FRANK TYGER, POLITICAL CARTOONIST AND COLUMNIST I

Thus it becomes obvious that one must be wary in attributing scientific discovery wholly to any one person. Almost every discovery has a long and precarious history. Someone finds a bit here, another a bit there. A third step succeeds later and thus onward till a genius pieces the bits together and makes the decisive contribution.

Creativity requires risk. So do exploration and innovation. Anyone who thinks outside of the box is taking a risk. Leadership brings many risk. Courage is exercised in the face of risk. Invest involve risk. Decision-making always mean a certain degree of risk.

Discovery is the ability to be puzzled by simple things.

Every new set of discoveries raises a host of questions which we were never before wise enough even to ask.

In life, as in science, the greatest discoveries are made by those who dare to persist when the path gets tough. It’s about pushing forward when others might give up, navigating uncertainty with determination and vision.

Every significant invention must be startling, unexpected, and must come into a world that is not prepared for it. If the world were prepared for it, it would not be much of an invention.