The basic challenge to mankind is not population, poverty, war, technology, pollution, religious or racial intolerance, or blind nationalism, but an … - Lancelot Law Whyte

I consider that Curie's Principle has two major consequences:-
First: It shows that the class of processes which can be isolated for causal representation, not requiring the inference of external causes, is wider than the class of energetically closed systems. One-way processes in which the system loses energy can be isolable, in the sense that they can be given complete representation without taking their environment into account.
Second: It suggests the possibility of a geometrical physics treating 3D spatial relations , i.e., angles or lengths, as primary. Just as statistical mechanics, the theory of crystal symmetry, and Group theory in quantum mechanics, are useful without assumptions about forces, so Curie's principle, with an appropriate model, can determine the path of a one-way process without such assumptions...

During the metamorphosis from ancient to European man, self-awareness, rationalism, monotheism, and morality all developed in parallel as expressions of the influence of a new form of social tradition on the organization of the individual. […] Europe forced the new mode of life till it produced a definite dissociation, for self-awareness did not then bring with it an adequate understanding of the self; religion could not offer a complete integration; the rational intellect knew nothing of its own origins, limitations or mode of operation; and morality necessarily failed to realize its aim. (p. 114)

A clue to the future must lie in the past... every scientist, and everyone with intellectual curiosity, can learn something useful from a brief study of the history of atomism.