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Patients with uncontrolled epilepsy have an evaluation that usually begins with electrical studies of the surface of the brain. …A hole is drilled in… - Richard Bergland
" "Patients with uncontrolled epilepsy have an evaluation that usually begins with electrical studies of the surface of the brain. …A hole is drilled in the skull, and electrical measurements made from within the depths of the brain. A large flap of the skull is then lifted up, electrodes placed on the surface of the brain, and the flap sewn back into place so that more electrical studies can be done. The risks... are far greater than those associated with the ventricular taps needed for hormone studies. …If the team of doctors.. can help... areas of the brain that are sending 'bad' signals would be identified and removed... large portions of the brain might be taken away.
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About Richard Bergland
Richard M. Bergland (1932 - 2007) was an author, administrator, neurosurgeon and neuroscientist. He was chief of neurosurgery at Beth Israel Hospital of New York. He was also a Van Wagenen Scholar, a Markle Scholar and Macy Faculty Scholar and served academic appointments at Oxford, Harvard, Cornell and Columbia, among others.
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Despite the evidence that ventricular hormones do not make their way out of the ventricle, the presence of large ventricles in many schizophrenic patients, and the ability of two-dimensional gels to provide a profile of peptides in the ventricle, not a single catheter has been placed into the ventricle of a schizophrenic patient to measure the peptides in the ventricle. ...There is no animal model for this disease, the answer can only come from human studies.
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