As is known, scientific physics dates its existence from the discovery of the differential calculus. Only when it was learned how to follow continuously the course of natural events, attempts, to construct by means of abstract conceptions the connection between phenomena, met with success. To do this two things are necessary: First, simple fundamental concepts with which to construct; second, some method by which to deduce, from the simple fundamental laws of the construction which relate to instants of time and points in space, laws for finite intervals and distances, which alone are accessible to observation (can be compared with experience).

II. Thesis. In order that decision by arbitrary power may be possible in spite of completely definite laws of the action of ideas, one must assume that the psychic mechanism itself has, or at least in its development acquires, the peculiar property of inducing the necessity of these laws. Antithesis. No one can, in case of affairs, abandon the conviction that the future is co-determined by his transactions.

Measure-relations can only be studied in abstract notions of quantity, and their dependence on one another can only be represented by formulæ. On certain assumptions, however, they are decomposable into relations which, taken separately, are capable of geometric representation; and thus it becomes possible to express geometrically the calculated results. In this way, to come to solid ground, we cannot, it is true, avoid abstract considerations in our formulæ, but at least the results of calculation may subsequently be presented in a geometric form. The foundations of these two parts of the question are established in the celebrated memoir of Gauss, Disqusitiones generales circa superficies curvas.

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It is absurd to assume that upon the rigid earth-crust the organic originated from the inorganic. In order to explain the nascence of the lowest organisms on the earth-crust, one must assume an already existing organising principle or a thought-process, under conditions that would render organic combinations impossible. We must accordingly assume that these conditions are valid only for the life-process in the actual state of the earth's surface, and only so far as we can explain them may we estimate the possibility of life-processes under other conditions.

If in the case of a notion whose specialisations form a continuous manifoldness, one passes from a certain specialisation in a definite way to another, the specialisations passed over form a simply extended manifoldness, whose true character is that in it a continuous progress from a point is possible only on two sides, forwards or backwards. If one now supposes that this manifoldness in its turn passes over into another entirely different, and again in a definite way, namely so that each point passes over into a definite point of the other, then all the specialisations so obtained form a doubly extended manifoldness. In a similar manner one obtains a triply extended manifoldness, if one imagines a doubly extended one passing over in a definite way to another entirely different; and it is easy to see how this construction may be continued. If one regards the variable object instead of the determinable notion of it, this construction may be described as a composition of a variability of n + 1 dimensions out of a variability of n dimensions and a variability of one dimension.

The word hypothesis has now a somewhat different significance from that given it by Newton. We are now accustomed to understand by hypothesis all thoughts connected with the phenomena.
Newton was far from the crude thought that explanation of phenomena could be attained by abstraction.

For Space, when the position of points is expressed by rectilinear co-ordinates, <math>ds = \sqrt{ \sum (dx)^2 }</math>; Space is therefore included in this simplest case. The next case in simplicity includes those manifoldnesses in which the line-element may be expressed as the fourth root of a quartic differential expression. ...I restrict myself... to those manifoldnesses in which the line element is expressed as the square root of a quadric differential expression. ...Manifoldnesses in which, as in the Plane and in Space, the line-element may be reduced to the form <math>\sqrt{ \sum (dx)^2 }</math>, are... only a particular case of the manifoldnesses to be here investigated; they require a special name, and therefore these manifoldnesses... I will call flat. In order now to review the true varieties of all the continua which may be represented in the assumed form, it is necessary to get rid of difficulties arising from the mode of representation, which is accomplished by choosing the variables in accordance with a certain principle.

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The method applied by Newton to the grounding of the Infinitesimal Calculus, and which since the beginning of this century has been recognised by the best mathematicians as the only one that furnishes sure results, is the method of limits. The method consists in this, viz., instead of considering a continuous transition from one value of a quantity to another, from one position to another, or, speaking generally, from one determination of a concept to another, one considers in the first place a transition through a finite number of intervals and then allows the number of these intervals to increase so that the distances of two successive points of division all decrease infinitely.