I think a hero is an ordinary individual who finds the strength to persevere and endure in spite of overwhelming obstacles. The fifteen-year-old boy who landed on his head while wrestling with his brother, leaving him paralyzed and barely able to swallow or speak. Travis Roy, paralyzed in the first eleven seconds of a hockey game in his freshman year at college. Harry Steifel, paralyzed from the chest down in a car accident at seventeen, completing his education and working on Wall Street at age thirty-two, but having missed so much of what life has to offer. These are the real heroes, and so are the many families and friends who have stood by them.
American actor (1952–2004)
Christopher D'Olier Reeve (25 September 1952 – 10 October 2004) was an American actor, director, producer, writer, lobbyist, and husband of actress Dana Reeve. He is most famous for playing the role of Superman in the film Superman (1978) and its three sequels.
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Birth Name:
Christopher D'Olier Reeve
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I believe, throughout history, there has been common agreement in societies around the world that the life results because of the union of male and female. Whether it's done in a test tube, or whether it's done through intercourse. And fertilized embryos in clinics are still the union, result of the union of male and female. Therapeutic cloning takes an egg that is not fertilized, and is left in the cellular stage, in the very early stages, about three to five, seven days, then the nucleus is removed and the DNA from a patient. Either male or female can be put into it. Now, that is an aberrant life form. If you were to take it further and implant it, then only insane people would want to do that, in my opinion. But considering the fact that they're talking ... you're talking about the difference of life as we've understood it for hundreds of thousands of years, versus a collection of cells that will never become a human being, and I don't even believe deserves a status of the word embryo. It could be called a pseudo-embryo, it could be called, you know, some other name should come up from it, because just like test tube babies scared people before, the buzzword embryo scares people today. Cloning scares people today, but this is simply a manipulation of cells that are not equivalent to life as we've always known it.
On the other hand, you have to understand that our allies are not rogue nations. The U.K., Australia, Canada, Singapore, Israel, India, these are just some of the countries that have already passed therapeutic cloning. In fact, England passed it twice. The House of Lords considered it, passed it, the pro-life groups objected to it, they took time to listen to those groups and then they passed it a second time. And therapeutic cloning is allowed with strict government oversight. And to say that those countries are less moral than we are, I think is hubris on our part that's out of control.
[Y]ou have to understand that therapeutic cloning is a very nascent technology that's not ready for use in humans. But knowing that it will not . . . provided our scientists are allowed to go ahead with the research, it really shouldn't take that long before they're ready for humans. However, knowing that there is a better technology out there than just using embryonic stemcells, he as a doctor feels, given the immune rejection problem for people with spinal cord injuries, he's not going to go ahead, as he had planned to. There was a plan to actually use embryonic stem cells as soon as it would be allowed by the FDA. He is not going to do that until therapeutic cloning gets to the point where it could be applied to humans. And I just want to make one other very quick comment and that is in England, just a month ago, Dr. Ann Bishop, who works with the tissue engineering corporation over there, was able to take mouse embryonic stem cells that derived . . . had been made obviously therapeutic cloning, and they turned those cells into tissue that is applied to the lungs, to deficient cell types or cell tissues in the lungs, and said, have already reported, I guess it's public knowledge, that they feel they are now ready to do it in humans, so the idea that it would be decades before you could get to human application, I think that is one example I'm giving you right now of the fact that that's not true. I can give you another example. Doctor Oswald Stewart, of the Reeve Research Center, UC Irvine has said that you could probably get to the use of therapeutic cloning in humans within about three to five years. So I absolutely dispute the time line that's been put up before.
I work with Dr. John McDonald at Washington University in St. Louis, and he is a very knowledgeable researcher on (Inaudible) stem cells, and a few years ago he said to me that in order to cure my particular condition, which is demyelination of nerves in a very small area of the spinal cord, right at the second cervical vertebrae, that if you imagine the rubber coating around a wire that allows conductivity of electricity, the same thing as with nerves, myelin is like that rubber coating. It's a fatty substance that if it comes off of the nerves, then signals do not go from the brain down to the spinal cord as required. However, it is possible, and he's demonstrated this as graphic(?) as possible, to re-myelinate. Now, a few years ago, he said, we would be willing to inject human embryonic stem cells into you and hope for the best. But hoping for the best is a very dangerous proposition for people with spinal cord injuries because our spinal cord injury affects every organ in the body, and the most serious side effect is that it severely compromises the immune system, so spinal cords patients, particularly with high level injuries like mine, are prone first to pneumonia, which I've had at least five times since my injury, many patients often die from that. Also, it compromises the cardiovascular system, compromises the digestive tract, the ... your whole bowel-bladder-sexual function, skin integrity and also bone density, so that osteoporosis becomes a very ... a very critical factor. So literally he said to me that the immunosuppression that would be required just to inject 30million human embryonic stem cells from an anonymous donor might kill me. And now, he would be unwilling as a doctor, because of the ethics involved that a doctor is ethically bound to give his patients the best possible treatment, he would not inject me with embryonic stemcells unless we go the other route, which is therapeutic cloning- taking an egg, removing the nucleus, taking DNA from my skin and deriving stem cells from that, which would be injected in a manner that would probably not be rejected by my immune system. So my future, and others would agree, many scientists would agree, my future, in terms of being able to recover will depend on some way of delivering stem cells without compromising my immune system and therapeutic cloning, which would use my DNA is the best hope.
[N]ever in the history of science have we been given such a gift of being able to use cells that can become any tissue or cell type in the body for the purpose of healing. I think that if you do not have the combination of therapeutic cloning and embryonic stem cells, you are going to be condemning a lot of people to unnecessary and death. If I look around at what else is going on, for years just in the spinal cord community, there has been research on growth factors and Schwann cells, and there have been efforts to stop protein inhibitor, but they have not yet shown the same promise that the embryonic stem cells do, and at the moment, in two places, Washington University in St. Louis and the University of California at Irvine, researchers have been conducting very successful experiments using human embryonic stem cells in animal models in both the acute and chronic phases and getting recovery. Of course, they are going to have to move to the higher animal forms before humans, but the promise is absolutely extraordinary, and I cannot think of any other kind of therapy that would be as effective and as promising as this is. And when I read articles or hear people say that the promise of human embryonic stem cells is dubious, I am very disturbed, because the only reason they get to say that is because the NIH has not been allowed to spend a single dollar on embryonic stem cell research. They have a budget now of $25 billion, and yet, because of lack of guidelines and because of the restrictions that have been imposed on the NIH so far, not one human embryonic stem cell project has been federally funded. That is why you are seeing such slow progress. And if we continue that way, I am going to be in this wheelchair for a long time that I do not need to be, and others like me.
[A] scientist at Washington University, Dr. John McDonald, whom I have been working with says that there is no way he would inject stem cells without being able to use my own DNA for safety reasons. So without the ability to use my own DNA, without that somatic cell transfer, I am out of luck. The other thing is to please remember that therapeutic cloning, nucleus transplantation, is done with unfertilized eggs. You keep referring to destroying an embryo. I think that destroying an embryo is what happens when the leftovers from fertility clinics are thrown out. We can agree that they go to the garbage routinely. But to say that an unfertilized egg has the same status, I believe is incorrect, and I think that this is the line of research that holds so much promise and can also get us around the ethical quandary that we keep putting ourselves in. We are talking about an unfertilized egg that will never leave the lab, that will never be implanted in a womb, and that can be regulated. And it is crucial for research.
I need to object, and that is that, Senator, you insist on separating therapeutic cloning and embryonic stem cells. However, in my own case, I require re-myelination of nerves. That means replacing the conductive coat of fat, myelin, that allows electricity to come down, currents from the brain to the central nervous system for function. At the moment, only embryonic stem cells have the potential to do that, and experiments are being done now in larger animals demonstrating that.
[J]ust on a daily basis, the Government is saying to people that, yes, there is a threat of terror, but fly and go to the theater and live your life and take that risk, because every day, you hear about fighter escorts having to take some airplane back to the airport because there was another bomb threat. People are boarding airplanes, passing security checkpoints, and then found to be carrying dangerous material - but still we go on. So yes, you take a risk that somebody somewhere could get involved in creating a human out of reproductive cloning, but it is not at all likely, and to be afraid of pursuing therapeutic cloning is really going to be reprehensible, because you cannot use embryonic stem cells for therapy without being able to use therapeutic cloning — it will not work.
If you believe in the slippery slope here, it means that our entire society is perched on the slippery slope. It means that regulation has no value whatsoever, and that is not true. Now, there are always consequences. We allow 16-year-olds to get driver's licenses, and a lot of them have accidents - but do we rescind the permission to drive a car at 16? No.
Today, human trials to defeat Parkinson's are underway in Sweden. In Israel, macrophages, scavenger cells that eat debris in the body, are being used to repair the damaged spinal cord within 2 weeks of injury. The first human subject was a 19-year-old girl from Colorado. Last week, the House of Lords in the United Kingdom passed legislation permitting research on cloned human embryos for the second time. Those are not rogue nations behaving irresponsibly. They are allies, no less moral than we are.