Eric Kandel Quotes

Cori Bargmann... has studied two variants of C. elegans... The only difference between the two is one amino acid in an otherwise shared receptor protein. Transferring the receptor from a social worm to a solitary worm makes the solitary worm social.

The idea that we are unaware of much of out mental life, first developed by Hermann Helmholtz, is central to psychoanalysis. Freud has added the interesting idea that although we are not aware of most instances of mental processing, we can gain conscious access... by paying attention.

I would like to develop a reductionist approach to the problem of attention by focusing on how place cells... create an enduring spatial map only when an organism is paying attention to its surroundings.

...in various types of organisms, from snails to flies to mice to people. ...learning and memory, as well as synaptic and neuronal plasticity, represent a family of processes that share a common logic and some key components but vary in the details of their molecular mechanisms.

We now understand that every mental state and every mental disorder is a disorder of brain function. Treatments work by altering the structure and function of the brain.

I have at times felt alone, uncertain, without a well-trodden path to follow. Every time I embarked on a new course, there were well-meaning people... who advised against it. I had to learn early on to be comfortable with insecurity and to trust my own judgement on key issues.

The life of a biological scientist in the United States is a life of discussion and debate—it is the Talmudic tradition writ large. ...The egalitarian structure of American science encourages this camaraderie. ...this would not—could not—have taken place in the Austria, the Germany, the France, or perhaps even the England of 1955.

I was astonished to discover that working in the laboratory—doing science in collaboration with interesting and creative people—is dramatically different from taking courses and reading about science.

I continue to explore the science in which I work almost like a child, with naïve joy, curiosity, and amazement.

My hope is that the difference in the three generations' attitudes may signal a lessening of anti-Semitism in Austria.

The Viennese Kultusgemeinde... was going bankrupt... European governments typically compensate Jewish agencies... but the Austrian government's compensation was not adequate. ...I owe my existence in the United States to the generosity of the Viennese Kultusgemeinde.

The history of Austrian culture and scholarship in the modern era largely paralleled the history of Austrian Jewry.

Pernkopf was only one of many Austrians who were "rehabilitated" in the postwar period. Their rehabilitation underscores the tendency of Austria to forget, suppress, and deny the events of the Nazi period. ...Anton Pelinka ...has called this phenomenon the "great Austrian taboo." It is precisely this moral vacuum that induced Simon Wiesenthal to establish his documentation center for Nazi war crimes in Austria, not Germany.

By merely observing the electrical activity in the brain, Libet could predict what a person would do before the person was actually aware of having decided to do it. This finding caused philosophers of mind to ask: If the choice is determined in the brain before we decide to act, where is free will? ...choice in action, as in perception, may reflect the importance of unconscious inference. Libet proposes that... just before the action is initiated, consciousness is recruited to approve or veto the action.

Unlike vision, touch, or smell, which are prewired and based on Kantian a priori knowledge, the spatial map presents us with a new type of representation, one based on a combination of a priori knowledge and learning. The general capability for forming spatial maps is built into the mind, but the particular map is not. Unlike neurons in a sensory system, place cells are not switched on by sensory stimulation. Their collective activity represents the location where the animal thinks it is.