Unless you experience the unpleasant symptoms of being wrong, your brain will never revise its models. Before your neurons can succeed, they must repeatedly fail. There are no shortcuts for this painstaking process.

Suffering through his classes, the young Igor steeped himself in angst. He would later describe his childhood as 'a period of waiting for the moment when I could send everyone and everything connected with it to hell.

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The fatal misconception behind brainstorming is that there is a particular script we should all follow in group interactions.... [W]hen the composition of the group is right — enough people with different perspectives running into one another in unpredictable ways — the group dynamic will take care of itself. All these errant discussions add up. In fact, they may even be the most essential part of the creative process. Although such conversations will occasionally be unpleasant — not everyone is always in the mood for small talk or criticism — that doesn’t mean that they can be avoided. The most creative spaces are those which hurl us together. It is the human friction that makes the sparks.

After all, we're a brain embedded in this larger set of structures. You can call it culture, call it society, call it your family, call it your friend, call it whatever it is. It's the stuff that makes people sign onto their Facebook a thousand times a day. It's the reason Twitter exists. We have got all these systems now that really make us fully aware of just how important social interactions are to what it is to be human. The question is, how can we study that? Because that, in essence, is a huge part of what's actually driving these enzymatic pathways in your brain. What's triggering these synaptic transmissions and these squirts of neurotransmitter back and forth is thoughts of other people, what other people say to us, interacting with the world at large.

In fact, even fleeting feelings of delight can lead to dramatic increases in creativity. After watching a short, humorous video — Beeman uses a clip of Robin Williams doing standup — subjects have significantly more epiphanies, at least when compared with those who were shown scary or boring videos. Because positive moods allow us to relax, we focus less on the troubling world and more on these remote associations. Another ideal moment for insights, according to Beeman and John Kounios, is the early morning, shortly after waking up. The drowsy brain is unwound and disorganized, open to all sorts of unconventional ideas. The right hemisphere is also unusually active.

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You break out of the box by stepping into shackles.
From Imagine: How Creativity Works pg 23 (hardcover)

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Science has discovered that, like any work of literature, the human genome is a text in need of commentary, for what Eliot said of poetry is also true of DNA: 'all meanings depend on the key of interpretation.' What makes us human, and what makes each of us his or her own human, is not simply the genes that we have buried into our base pairs, but how our cells, in dialogue with our environment, feed back to our DNA, changing the way we read ourselves. Life is a dialectic.

People assume that they perceive reality as it is, that our senses accurately record the outside world. Yet the science suggests that, in important ways, people experience reality not as it is, but as they expect it to be.

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For too long, people have disparaged the emotional brain, blaming
our feelings for all of our mistakes. The truth is far more interesting.
What we discover when we look at the brain is that the
horses and the charioteer depend upon each other. If it weren't
for our emotions, reason wouldn't exist at all.