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Is the very mechanism for the universe to come into being meaningless or unworkable or both unless the universe is guaranteed to produce life, consciousness and observership somewhere and for some little time in its history-to-be? The quantum principle shows that there is a sense in which what the observer will do in the future defines what happens in the past—even in a past so remote that life did not then exist, and shows even more, that 'observership' is a prerequisite for any useful version of 'reality'.

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Of all obstacles to a thoroughly penetrating account of existence, none looms up more dismayingly than “time.” Explain time? Not without explaining existence. Explain existence? Not without explaining time. To uncover the deep and hidden connection between time and existence, to close on itself our quartet of questions, is a task for the future.

It from bit symbolizes the idea that every item of the physical world has at bottom — at a very deep bottom, in most instances — an immaterial source and explanation; that which we call reality arises in the last analysis from the posing of yes-no questions and the registering of equipment-evoked responses; in short, that all things physical are information-theoretic in origin and that this is a participatory universe.

I had the good fortune of having my first and only heart attack last January ... I call it good fortune because it taught me that there's a limited amount of time left and I better concentrate on one thing: How come existence? How come the quantum? Maybe those questions sound too philosophical, but maybe philosophy is too important to be left to the philosophers.

For all our everyday experience, the geometry of space is smooth and flat. But as we examine it more closely, it must show oscillations. And still more closely, it must show foam, a foam-like structure. And that means that down at the very smallest distances, this idea of before and after really lose their meaning.

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Today I think we are beginning to suspect that man is not a tiny cog that doesn’t really make much difference to the running of the huge machine, but rather that there is a much more intimate tie between man and the universe than we heretofore suspected…The physical world is in some deep sense tied to the human being.