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Ten years later we actually have done that people are increasingly doing risk assessment in their practices, they are counseling women about their familial risk, and they are offering interventions that have been lifesaving for many women from high-risk families.”

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We’ve been very interested in familial breast cancer and the contribution of genes like BRCA1 and BRCA2 that predispose families to breast cancer. We’re very interested in looking at the genetic basis of breast cancer in young women. As a result of that investigation, we’re hoping to develop better tools and better methods to manage triple-negative breast cancer, because that’s what we see to be over-represented in young African American women and women with BRCA1 mutations.

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Triple-negative breast cancer is not the majority of breast cancer. But if we have drugs that can target the genetic abnormalities in these tumors, and we are able to rapidly conduct global clinical trials, not only can we get studies done quickly, but we can also make it possible for women all over the world to participate in the cures of tomorrow.