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During the renaissances in thinking led by Shakespeare and Goethe, the first new development in memory techniques for 1,700 years appeared: the Major System. This was the first system that enabled the user to transfer easily and instantaneously from numbers to letters, thus creating the opportunity for a system that could stretch from zero to an infinite number, and which allowed the user to translate any word into its own special number, and any number into its own special letter. This multiplied the opportunity for developing memory techniques 100-fold.

The old linear pattern of thinking by reading and describing from left to right, top to bottom has many problems in organizing information coming from eyes, ears, etc. For example, the ability to read and understand the context of a book is different from memorizing them simply as sentences.

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As knowledge of the alphabet and its permutations and combinations is to traditional literacy, and as a knowledge of numbers and their permutations and combinations is to mathematics, so a knowledge of the biological and conceptual alphabets of the brain and its apparently infinite permutations and combinations is to mental literacy.