Laplace made many important discoveries in mathematical physics... Indeed, he was interested in anything that helped to interpret nature. He worked o… - Morris Kline

To the scientists of 1850, Hamilton's principle was the realization of a dream. ...from the time of Galileo scientists had been striving to deduce as many phenomena of nature as possible from a few fundamental physical principles. ...they made striking progress ...But even before these successes were achieved Descartes had already expressed the hope and expectation that all the laws of science would be derivable from a single basic law of the universe. This hope became a driving force in the late eighteenth century after Maupertuis's and Euler's work showed that optics and mechanics could very likely be unified under one principle. Hamilton's achievement in encompassing the most developed and largest branches of physical science, mechanics, optics, electricity, and magnetism under one principle was therefore regarded as the pinnacle of mathematical physics.

The goal of deriving all the phenomena of nature from a few basic physical laws and the axioms of mathematics had been set by Galileo...
In studying curvilinear motions on the earth Galileo had found the parabola to be the basic curve. In the heavens... Kepler... had found the ellipse to be the basic curve. Why this difference? ...since parabola and ellipse are both conic sections there was the provocative suggestion that perhaps some physical law unified these related paths of motion. ...
It has often happened in the history of mathematics and science that major problems remained outstanding... great minds... succeeded only in revealing the true difficulties... and in generating an atmosphere of dispair... Then a genius appeared... with ideas that seemed remarkably simple once propounded, clarified the entire situation, dispelled the confusion, restored order, and produced a new synthesis that embraced far more even than the phenomena under consideration. The genius who... picked up the torch of science dropped by Galileo, was Isaac Newton.

The minimum principle that unified the knowledge of light, gravitation, and electricity of Hamilton's time no longer suffices to relate these fundamental branches of physics. Within fifty years of its creation, the belief that Hamilton's principle would outlive all other physical laws of physics was shattered. Minimum principles have since been created for separate branches of physics... but these are not only restricted... but seem to be contrived... A single minimum principle, a universal law governing all processes in nature, is still the direction in which the search for simplicity is headed, with the price of simplicity now raised from a mastery of differential equations to a mastery of the calculus of variations.