The goal of deriving all the phenomena of nature from a few basic physical laws and the axioms of mathematics had been set by Galileo... In studying … - Morris Kline

The Hindus introduced negative numbers... The first known use is about 628; he also states the rules for the four operations with negative numbers. Bhāskara points out that the square root of a positive number is twofold, positive and negative. He brings up the matter of the square root of a negative number but says that there is no square root because a negative number is not a square. No definitions, axioms, or theorems are given.
The Hindus did not unreservedly accept negative numbers. Even Bhāskara, while giving 50 and -5 as two solutions of a problem, says, "The second value is in this case not to be taken, for it is inadequate; people do not approve of negative solutions." However, negative numbers gained acceptance slowly.

The minimum principle that unified the knowledge of light, gravitation, and electricity of Hamilton's time no longer suffices to relate these fundamental branches of physics. Within fifty years of its creation, the belief that Hamilton's principle would outlive all other physical laws of physics was shattered. Minimum principles have since been created for separate branches of physics... but these are not only restricted... but seem to be contrived... A single minimum principle, a universal law governing all processes in nature, is still the direction in which the search for simplicity is headed, with the price of simplicity now raised from a mastery of differential equations to a mastery of the calculus of variations.

Aristotle had considered the question of whether space is infinite and gave six nonmathematical arguments to prove that it is finite; he foresaw that this question would be troublesome.