Aristotle had considered the question of whether space is infinite and gave six nonmathematical arguments to prove that it is finite; he foresaw that… - Morris Kline

To the scientists of 1850, Hamilton's principle was the realization of a dream. ...from the time of Galileo scientists had been striving to deduce as many phenomena of nature as possible from a few fundamental physical principles. ...they made striking progress ...But even before these successes were achieved Descartes had already expressed the hope and expectation that all the laws of science would be derivable from a single basic law of the universe. This hope became a driving force in the late eighteenth century after Maupertuis's and Euler's work showed that optics and mechanics could very likely be unified under one principle. Hamilton's achievement in encompassing the most developed and largest branches of physical science, mechanics, optics, electricity, and magnetism under one principle was therefore regarded as the pinnacle of mathematical physics.

Brook Taylor... in his Methodus Incrementorum Directa et Inversa (1715), sought to clarify the ideas of the calculus but limited himself to algebraic functions and algebraic differential equations. ...Taylor's exposition, based on what we would call finite differences, failed to obtain many backers because it was arithmetical in nature when the British were trying to tie the calculus to geometry or to the physical notion of velocity.

The goal of deriving all the phenomena of nature from a few basic physical laws and the axioms of mathematics had been set by Galileo...
In studying curvilinear motions on the earth Galileo had found the parabola to be the basic curve. In the heavens... Kepler... had found the ellipse to be the basic curve. Why this difference? ...since parabola and ellipse are both conic sections there was the provocative suggestion that perhaps some physical law unified these related paths of motion. ...
It has often happened in the history of mathematics and science that major problems remained outstanding... great minds... succeeded only in revealing the true difficulties... and in generating an atmosphere of dispair... Then a genius appeared... with ideas that seemed remarkably simple once propounded, clarified the entire situation, dispelled the confusion, restored order, and produced a new synthesis that embraced far more even than the phenomena under consideration. The genius who... picked up the torch of science dropped by Galileo, was Isaac Newton.