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When we have found how the nucleus of atoms is built up we shall have found the greatest secret of all — except life. We shall have found the basis of everything — of the earth we walk on, of the air we breathe, of the sunshine, of our physical body itself, of everything in the world, however great or however small — except life.

The first point that arises is the atom. I was brought up to look at the atom as a nice hard fellow, red or grey in colour, according to taste. In order to explain the facts, however, the atom cannot be regarded as a sphere of material, but rather as a sort of wave motion of a peculiar kind. The theory of wave-mechanics, however bizarre it may appear... has the astonishing virtue that it works, and works in detail, so that it is now possible to understand and explain things which looked almost impossible in earlier days. One of the problems encountered is the relation between the electron, an atom and the radiation produced by them jointly; the new mechanics states the type of radiation emitted with correct numerical relations. When applied to the periodic table, a competent and laborious mathematician can predict the periodic law from first principles.

It is not in the nature of things for any one man to make a sudden violent discovery; science goes step by step, and every man depends on the work of his predecessors. When you hear of a sudden unexpected discovery—a bolt from the blue, as it were—you can always be sure that it has grown up by the influence of one man on another, and it is this mutual influence which makes the enormous possibility of scientific advance. Scientists are not dependent on the ideas of a single man, but on the combined wisdom of thousands of men, all thinking of the same problem, and each doing his little bit to add to the great structure of knowledge which is gradually being erected.

...Rutherford never spent more than £2500 a year on his research programme. He resisted suggestions that an industrial appeal might provide him with more money and he did not believe in the economic significance of any of the work he was doing. He used to boast that ‘we have no money, so we shall have to think’.

We may in these processes obtain very great quantities of energy, but on the average we cannot hope to obtain energy for practical use in this way. The bombardment of the atom is a very poor and inefficient way of producing energy and anyone who is looking for a source of cheap power in the transformation of the atom, is talking pure moonshine... Some day the knowledge we may gain may be of practical value, but there is no indication of it yet.