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On the other side of anger at those who either peddled false visions of security or incited irrational fears of death, Lucretius offered a feeling of liberation and the power to stare down what had once seemed so menacing. What human beings can and should do, he wrote, is to conquer their fears, accept the fact that they themselves and all the things they encounter are transitory, and embrace the beauty and the pleasure of the world.

Tyrannical power is more easily exercised when it appears that the old order continues to exist. The reassuring consensual structures may now be hollowed out and merely decorative, but they are all still in place, so that the bystanders, who crave psychological security and a sense of well-being, can persuade themselves that the rule of law is being upheld.

Poggio Bracciolini was a book hunter, perhaps the greatest in an age obsessed with ferreting out and recovering the heritage of the ancient world. The finding of a lost book does not ordinarily figure as a thrilling event, but behind that one moment was the arrest and imprisonment of a pope, the burning of heretics, and a great culturewide explosion of interest in pagan antiquity. The act of discovery fulfilled the life’s passion of a brilliant book hunter. And that book hunter, without ever intending or realizing it, became a midwife to modernity.

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There was a time in the ancient world—a very long time—in which the central cultural problem must have seemed an inexhaustible outpouring of books. Where to put them all? How to organize them on the groaning shelves? How to hold the profusion of knowledge in one’s head? The loss of this plenitude would have been virtually inconceivable to anyone living in its midst. Then, not all at once but with the cumulative force of a mass extinction, the whole enterprise came to an end. What looked stable turned out to be fragile, and what had seemed for all time was only for the time being.

This was the crucial moment in the development of the English language, the moment in which the deepest things, the things upon which the fate of the soul depended, were put into ordinary, familiar, everyday words. Two men above all others, William Tyndale and Thomas Cranmer, rose to the task. Without them, without the great English translation of the New Testament and the sonorous, deeply resonant Book of Common Prayer, it is difficult to imagine William Shakespeare.

Something happened in the Renaissance, something that surged up against the constraints that centuries had constructed around curiosity, desire, individuality, sustained attention to the material world, the claims of the body. The cultural shift is notoriously difficult to define, and its significance has been fiercely contested. But it can be intuited easily enough when you look in Siena at Duccio’s painting of the enthroned Virgin, the Maestà, and then in Florence at Botticelli’s Primavera.

Shakespeare did not think that tyrants ever lasted for very long. However cunning they were in their rise, once in power they were surprisingly incompetent. Possessing no vision for the country they ruled, they were incapable of fashioning enduring support, and though they were cruel and violent, they could never crush all of the opposition. Their isolation, suspicion, and anger, often conjoined to an arrogant overconfidence, hastened their downfall. The plays that depict tyranny inevitably end at least with gestures toward the renewal of community and the restoration of legitimate order.

A comparably capacious embrace of beauty and pleasure—an embrace that somehow extends to death as well as life, to dissolution as well as creation—characterizes Montaigne’s restless reflections on matter in motion, Cervantes’s chronicle of his mad knight, Michelangelo’s depiction of flayed skin, Leonardo’s sketches of whirlpools, Caravaggio’s loving attention to the dirty soles of Christ’s feet.

Populism may look like an embrace of the have-nots, but in reality it is a form of cynical exploitation. The unscrupulous leader has no actual interest in bettering the lot of the poor. Surrounded from birth with great wealth, his tastes run to extravagant luxuries, and he finds nothing remotely appealing in the lives of underclasses. In fact, he despises them, hates the smell of their breath, fears that they carry diseases, and regards them as fickle, stupid, worthless, and expendable. But he sees that they can be made to further his ambitions.