As for negative numbers... most mathematicians of the sixteenth and seventeenth centuries did not accept them... In the fifteenth century and, in the… - Morris Kline

To the scientists of 1850, Hamilton's principle was the realization of a dream. ...from the time of Galileo scientists had been striving to deduce as many phenomena of nature as possible from a few fundamental physical principles. ...they made striking progress ...But even before these successes were achieved Descartes had already expressed the hope and expectation that all the laws of science would be derivable from a single basic law of the universe. This hope became a driving force in the late eighteenth century after Maupertuis's and Euler's work showed that optics and mechanics could very likely be unified under one principle. Hamilton's achievement in encompassing the most developed and largest branches of physical science, mechanics, optics, electricity, and magnetism under one principle was therefore regarded as the pinnacle of mathematical physics.

Over and above the specific theorems created by men such as Desargues, Pascal and La Hire, several new ideas and outlooks were beginning to appear. The first is the idea of continuous change of a mathematical entity from one state to another... [i.e., of a] a geometrical figure. It was Kepler, in his Astronomiae Optica of 1604, who first seemed to grasp the fact that parabola, ellipse, hyperbola, circle, and the degenerate conic consisting of a pair of lines are continuously derivable from each other. ...The notion of a continuous change in a figure was also employed by Pascal. He allowed two consecutive vertices of his hexagon to approach each other so that the figure became a pentagon. In the same manner he passed from pentagons to quadrilaterals.
The second idea to emerge from the work of the projective geometers is that of transformation and invariance. To project a figure from some point and then take a section of that projection is to transform the figure to a new one. The properties... of interest are those that remain invariant under transformation. Other geometers of the seventeenth century, for example, Gregory of St. Vincent... and Newton, introduced transformations other than projection and section.

Descartes... complained that Greek geometry was so much tied to figures "that is can exercise the understanding only on condition of greatly fatiguing the imagination." Descartes also deplored that the methods of Euclidean geometry were exceedingly diverse and specialized and did not allow for general applicability. Each theorem required a new kind of proof... What impressed Descartes especially was that algebra enables man to reason efficiently. It mechanizes thought, and hence produces almost automatically results that may otherwise be difficult to establish. ...historically it was Descartes who clearly perceived and called attention to this feature. Whereas geometry contained the truth about the universe, algebra offered the science of method. It is... paradoxical that great thinkers should be enamored with ideas that mechanize thought. Of course, their goal is to get at more difficult problems, as indeed they do.