There are reasons we become ill or dispirited. It's what Oriwia was referring to. There's always a cause. Sometimes we bring sickness or punishment upon ourselves through carelessness, distraction, transgression, or failing to dedicate the day or the task. Weak moments may invite wrong forces.
Sometimes sickness is caused by a vengeful person such as Oriwia describes. I have seen those affected by the spite of others become ill, go mad, become lame, turn black, drop dead, die slowly. I have seen their children born with ailments and deformities. (Chapter 25 p198)

Because the world is in a sick condition and we are all somehow infected, against our will, even if we think we are whole in mind and soul and body.

An illness is a failure to solve a mental or psychological problem in the correct manner . . . The energy that would be used to solve the problem instead is spent maintaining the illness. It is therefore necessary that an attempt be made as soon as possible to solve the problem, which of course must first be discovered by the ego, which has avoided it.

An organization belongs on a sick list when promotion becomes more important to its people than accomplishment of their job they are in. It is sick when it is more concerned with avoiding mistakes than with taking risks, with counteracting the weaknesses of its members than with building on their strength. But it is sick also when "good human relations" become more important than performance and achievement.

An organism at war with itself is doomed.

Philosophy can make people sick.

You make yourself sick.

If the essential core of the person is denied or suppressed, he gets sick sometimes in obvious ways, sometimes in subtle ways, sometimes immediately, sometimes later.

To think is to be sick.

Sickness occurs when we desire what we need and what's desirable with equal intensity, suffering our lack of perfection as if we were suffering for lack of bread.

Illnesses can be seen as impending actions representing actual blockages of energy, ation turned into channels that are not to the best interests of the personality. The energies appear concentrated and turned inward, affecting the whole system.

When the man who feeds the world by toiling in the fields is himself deprived of the basic rights of feeding, sheltering, and caring for his own family, the whole community of man is sick.

When we see a great man desiring power instead of his real goal we soon recognize that he is sick, or more precisely that his attitude to his work is sick. He overreaches himself, the work denies itself to him, the incarnation of the spirit no longer takes place, and to avoid the threat of senselessness he snatches after empty power. This sickness casts the genius on to the same level as those hysterical figures who, being by nature without power, slave for power, in order that they may enjoy the illusion that they are inwardly powerful, and who in this striving for power cannot let a pause intervene, since a pause would bring with it the possibility of self-reflection and self-reflection would bring collapse.

You are not sick because you have a disease; you have a disease because you are sick.