It doesn't matter how beautiful your theory is ... If it doesn't agree with experiment, it's wrong.

If the fact will not fit the theory - let the theory go

It doesn't matter how beautiful your theory is, it doesn't matter how smart you are. If it doesn't agree with experiment, it's wrong.

Never trust an experimental result until it has been confirmed by theory

When the fact doesn't meet the theory then let go the theory.

We must conduct research and then accept the results. If they don't stand up to experimentation, Buddha's own words must be rejected.

If the evidence says you’re wrong, you don’t have the right theory. You change the theory, not the evidence.

A theory is something nobody believes, except the person who made it. An experiment is something everybody believes, except the person who made it.

If you can’t think of an observation that could disprove a theory, that theory simply isn’t scientific.

If a theory claims to be able to explain some phenomenon, but does not generate even an attempt at an explanation, then it should be banished.

If you’re doing an experiment, you should report everything that you think might make it invalid — not only what you think is right about it: other causes that could possibly explain your results; and things you thought of that you’ve eliminated by some other experiment, and how they worked — to make sure the other fellow can tell they have been eliminated.

Good luck to you and bad luck to your theories.

Lo único que pide la ciencia es que se apliquen los mismos niveles de escepticismo que al comprar un coche usado o al juzgar la calidad de un analgésico o una cerveza a través de los anuncios de la televisión.

You learn as you go, and I think the most important thing to remember is that you are not your failures. That was a hard pill for me to swallow and something I'm still working through but the scientific process is built on failing! We have a theory, we test it, and a lot of the times that theory is wrong. That doesn't mean you aren't smart or you shouldn't continue testing other theories! Scientific exploration would come to a screeching halt if at every failed theory a scientist would quit.