Music may be the activity that prepared our pre-human ancestors for speech communication and for the very cognitive, representational flexibility necessary to become humans.

The Harvard neuroscientist Gottfried Schlaug has shown that the front portion of the corpus callosum is significantly larger in musicians than in nonmusicians, and particularly for musicians who began their training early. ...Schlaug found that musicians tended to have larger cerebellums than nonmusicians, and an increased concentration of gray matter... responsible for information processing, as opposed to white matter, which is responsible for information transmission.

The argument is that there may be a cluster of genes that influences both outgoingness and musicality. If this were true, we would expect to find that deviations in one ability co-occur with deviations in the other, as we do in WS and ASD.

As a tool for the activation of specific thoughts, music is as good as language. The combination of the two—as best exemplified in the love song—is the best courtship of all.

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During the first six months or so of life... the infant brain is unable to clearly distinguish the source of sensory inputs; vision, hearing, and touch meld into a unitary perceptual representation. ...inputs from the various sensory receptors may connect to many different parts of the brain, pending pruning that will occur later in life. As Simon Baron-Cohen has described it, with all this sensory cross talk, the infant lives in a state of complete psychodelic splendor (without the aid of drugs).

Memory strength is also a function of how much we care about the experience. ...If I'm playing an instrument I like, and whose sound pleases me in and of itself... caring leads to attention, and together they lead to measurable neurochemical changes. Dopamine, the neurotransmitter associated with emotional regulation, alertness, and mood, is released, and the dopaminergic system aids in encoding the memory trace.

We may have had music before we had a word for it.

A gene that promotes nurturing behavior postcopulation could... spread throughout the population, to the extent that the offspring of people with the nurturing gene fare better, as a group, in the competition for resources and mates.

Collective music making... may have historically served to promote feelings of group togetherness and synchrony, and may have been an exercise for other social acts...

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Joni's genius is that she creates chords that are ambiguous, chords that have two or more different roots. ...Joni's music is as close to impressionist visual art as anything I've heard. ...harmonic complexity born out of her strict insistence that the music not be anchored in a single harmonic interpretation.

Joni uses a lot of alternate tunings; that is, instead of tuning the guitar in the customary way, she tunes the strings to pitches of her own choosing. ...Joni will talk compellingly and passionately about alternate tunings for hours, comparing them to different colors that van Gogh used in his paintings.