It is pretty well established that there is an overconfidence effect. ... You don't have the competence to assess your own competence. ... you need competence in order to assess your own competence. ... Everyone has the Dunning-Kruger effect.

As you study science, and really try to understand what is happening behind the curtain, not just reading the predigested press releases but actually talking to scientists or reading technical papers, you realize that ... it's always more complicated than you think. ... No measurement is simple. ... The way you make the comparison will address different issues.

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In fact, there are many altered brain states where people may have a very vivid experience, or at least a vivid memory of their experience, precisely because they have impaired brain function. When you start dropping some of the higher brain functions out of the loop, like reality testing and things like that, … things can seem hyper-real. That could actually be a sign of brain dysfunction. It's similar to … somebody who is stoned thinking that they are really profound.

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… our inherent assumption is that you convince people with rational arguments. But all the data shows that most people are not influenced by rational arguments. They're influenced by social pressure. … That's just the human condition, and we just have to acknowledge it and accept it.

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The inability to explain something doesn't mean that it is inexplicable. … Always consider the simplest things first. … The inability to explain it doesn't mean that it has to be something fantastical or alien, or that it's unexplainable.