Entropy means that everything falls apart, except knowledge.

Just as the constant increase of entropy is the basic law of the universe, so it is the basic law of life to be ever more highly structured and to struggle against entropy.

Nature never undertakes any change unless her interests are served by an increase in entropy.

The opposite of nature is impossible.

There's no comfort, it seems, in the world of objects.

When things don't change any longer, that's the end result of entropy, the heat-death of the universe. The more things go on moving, interrelating, conflicting, changing, the less balance there is—and the more life. I'm pro-life, George. Life itself is a huge gamble against the odds, against all odds! You can't try to live safely, there's no such thing as safety. Stick your neck out of your shell, then, and live fully! It's not how you get there, but where you get to that counts. What you're afraid to accept, here, is that we're engaged in a really great experiment, you and I. We're on the brink of discovering and controlling, for the good of all mankind, a whole new force, an entire new field of antientropic energy, of the life-force, of the will to act, to do, to change!

But no one laughed. No one would. The universe, I’d learned, was never, ever kidding. It would take whatever it wanted and it would never give it back.

To make the existence and coherent structure of this Universe depend upon automatic activity and upon chance is against all good sense.

All theory is against the freedom of the will; all experience for it.

But no one laughed. No one would. The universe, I'd learned, was never, ever kidding. It would take whatever it wanted and it would never give it back.

Nature is monstrously unjust. There is no substitute for talent. Industry and all the virtues are of no avail.

It is almost impossible to substitute intelligence for experience.

Everybody wants to take something to eternity from this world, but there is nothing in this that can find a passage there except egolessness.

The law that entropy always increases, holds, I think, the supreme position among the laws of Nature. … if your theory is found to be against the second law of thermodynamics I can give you no hope; there is nothing for it but to collapse in deepest humiliation.